Predictive Inventory – Optimizing Drug Supply

Case Studies

The Challenge:

One of the greatest challenges in the conduct of a clinical trial is managing the expensive and often limited supply of investigational drug needed for the project. Anything that can help reduce waste and shipping costs while ensuring that clinical sites will have the drug they need when they need it is on the ‘most wanted’ list for the pharmaceutical industry. Since Interactive Response Technology (IRT) is one of the primary tools for drug assignment during a trial, the challenge has to be confronted by IRT vendors. How can control be achieved and maintained?

The Solution:

Veracity Logic’s Predictive Resupply algorithm is one of the tools for achieving efficient waste reduction while retaining an adequate drug supply where drug is needed. The algorithm takes into account a myriad of variables that impact on drug needs and timing. For example, the expected early withdrawal rate anticipated for a study can impact on the quantity of backlog maintained at a site for patient visits. Likewise, a study’s projected screen fail rate may determine the quantity of supply shipped to sites prior to randomization. The optimal number of inventory days at a site, the frequency of shipments desired by the sponsor, and shipping duration are also key impact variables that contribute to intelligent drug control.

Veracity Logic adds two more critical features to its proprietary predictive algorithm — the ability to control all key variables at the individual site level, and the ability to easily modify, on a configuration basis, the values assigned to each key variable throughout the clinical trial. In other words, we make Predictive Resupply sufficiently flexible to meet the changing, real-life needs of a study in progress.

Blinded Inventory View

Case Studies

Problem:

A variety of critical personnel involved in a clinical trial, including Sponsors, CROs, and Clinical Suppliers, need to keep track of the daily inventory of study drug and ancillary product available at each clinical site in the study. But the standard IRT inventory record includes data that unblinds. You need a fast way to provide site inventory status to those who need information, without a loss of study integrity. How to solve the dilemma?
Solution:

Veracity Logic’s IRT has been developed over ten years of experience with issues exactly like this one in mind. Our system can readily provide both a blinded and an unblinded inventory view of the Inventory page of your project. You specify the users who will have access to each type of inventory view. Unblinded users will see the number of kits of each treatment type available at each site. Blinded users will see a ‘rollup’ report of the total counts of all kits (including both study drug and ancillary kits) available at each site. Administrative (unblinded) users will be able to toggle between the two views.

This is just one more of the many ways Veracity Logic’s IRT provides the power and flexibility you need to meet real-life scenarios with real-life solutions.